Discussion of the dissertation of doctoral student

Discussion of the dissertation of doctoral student " Muhammad Obaid Ibrahim"

The public discussion took place for the Doctoral student (Muhammad Obaid Ibrahim) at Anbar University, College of Science, Department of Biology, on Thursday, 11, September 2025, in Ibn Sina Hall, for his tagged thesis

" Sequencing Analysis of Mobile Genetic Elements in Coagulase Negative Staphylococcus isolated from Nosocomial infections in Anbar Province"

The discussion committee consisted of:

University of Anbar - College of Sciences - President

Prof. Dr. Ahmed Abdul-Jabbar Suleiman

University of Fallujah - College of Medicine - Member

Prof. Dr. Liqaa Majeed Aziz

University of Anbar - College of Medicine - Member

Assist. Prof. Dr. Abdul-Rahman Mohammed Jiran

University of Anbar - College of Sciences - Member

Assist. Prof. Dr. Rana Talib Mohsen

University of Anbar - College of Sciences - member

Assist. Prof. Dr. Laith Musleh Najib

University of Anbar - College of Education for Pure Sciences - Member and Supervisor

Prof. Dr. Harith Kamel Biniyah

University of Anbar - College of Sciences - Member and Supervisor

Prof. Dr. Ali Hazem Abdul-Karim

 The study investigates the molecular epidemiology, resistance patterns, and genetic traits of coagulase-negative staphylococci, mainly S. epidermidis and S. haemolyticus. Using SCCmec typing and MLST, it identifies genetic lineages and virulence factors linked to device-related infections, aiming to support infection control and surveillance. A recent study revealed a wide genetic diversity among Staphylococcus epidermidis and Staphylococcus haemolyticus isolates in Iraq, with the first local documentation of novel sequence types (STs). Notably, the study identified ST23, ST59, ST89, ST35, and ST1183 for S. epidermidis, and ST24, ST35, ST109, ST173, and ST146 for S. haemolyticus.

The findings showed that MR-CoNS isolates exhibit high levels of antimicrobial resistance, particularly against beta-lactams, along with a strong ability to form biofilms, increasing the risk of device-associated infections. All isolates were positive for the mecA gene, while SCCmec typing revealed the predominance of types II, IV, and V.

Most importantly, the study documented 12 novel gene sequences, which were deposited in the GenBank database, marking the first genetic records from Iraq and strengthening the country’s contribution to the field of molecular and genetic research. These findings highlight the urgent need for enhanced molecular surveillance and targeted strategies to combat antimicrobial resistance, safeguard patients, and limit the spread of hard-to-treat infections.

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