Research Collaboration between the College of Science and the College of Dentistry – University of Anbar

Research Collaboration between the College of Science and the College of Dentistry – University of Anbar

Within the framework of academic research collaboration and the advancement of rigorous scientific inquiry, a joint research study entitled:

**“Dual Inhibitory Potential of Conessine Against HIV and SARS-CoV-2: Structure-Guided Molecular Docking Analysis of Critical Viral Targets”**

has been successfully completed and published.

The study was conducted by two collaborative research teams:

**Research Team from the Department of Biotechnology, College of Science:**

Prof. Dr. Safaa Abdul Latif Al-Muaini
Assist. Prof. Dr. Ali Hazem Abdul Karim
Assist.Lect. Mohammed Mukhlis Ahmed
Zaid Mustafa Khalil**

Research Team from the College of Dentistry:

Assist. Prof. Dr. Ilham Hazem Abdul Karim
Assist. Lect. Mina Thaer Al-Ani

The research investigated the **dual inhibitory role of the compound Conessine** as a potential therapeutic agent against two major viruses of global public health concern: **Human Immunodeficiency Virus type 1 (HIV-1)** and **Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)**. This was achieved through **structure-guided molecular docking and molecular dynamics (MD) simulations**.

The findings demonstrated **stable binding interactions of Conessine within the active sites of key viral enzymes**, indicating its promise as a candidate for the development of **multi-target, broad-spectrum antiviral agents**.

The study was published in the internationally renowned journal ***Viruses***, issued by **MDPI**, which is ranked **Q1** in the field of **Infectious Diseases** and is characterized by strong scientometric indicators:

* **Impact Factor:** 3.5
* **CiteScore:** 7.7

Moreover, the journal is indexed in leading international databases such as **PubMed** and **Scopus**, underscoring the **high scientific value and impact** of the published research in advancing contemporary antiviral and drug-discovery studies.
 

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